Women's Health Weekly
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Breast Cancer
Research from N. Altiok and co-researchers in the area of breast cancer published
July 3rd, 2008
According to recent research from the United States, "Cyclin D1 overexpression has been associated with poor prognosis and resistance to therapy in human breast cancer. Thus, the development of therapeutic agents that selectively target cyclin D1 activity is of clinical interest." "This study demonstrates that 12-oxo-phytodienoic acid (OPDA), a phytohormone with critical functions in growth and development in plants, induces growth arrest in MDA-MB-231 and T47D breast cancer cells. In response to OPDA treatment, the human breast cancer cell lines exhibit a progressive decline in cyclin D1 expression, which is tightly associated with the accumulation of...
Source: Women's Health Weekly (2008-07-03)
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