Women's Health Weekly
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Breast Cancer
Research from S. Haas and co-researchers yields new findings on breast cancer
July 3rd, 2008
According to recent research from Bonn, Germany, "The urokinase-type plasminogen activator (uPA) and the plasminogen activator inhibitor-1 (PAT-1) are involved in tumor invasion and metastasis as well as wound healing and inflammation. We investigated the impact of tissue injury by preoperative sampling on the level of uPA/PAI-1 in paraffin tissue of 55 breast cancer cases by immunohistochemistry." "The tumor area surrounding the biopsy channel was compared with distant intact tumor tissue. uPA and PAI-1 were constantly expressed by the tumor cells. Fibroblastic expression was higher in the tumor area surrounding the biopsy channel than in intact tissue with 47 vs 29...
Source: Women's Health Weekly (2008-07-03)
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