Women's Health Weekly
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Breast Cancer
New breast cancer study results reported from M. Rubenstein et al
July 10th, 2008
According to recent research from the United States, "Antisense oligonucleotides (oligos) against transforming growth factor-alpha (TGF-alpha) (MR1) and its binding site, the epidermal growth factor receptor (EGFR) (MR2), are efficacious against the UACC 897 breast, PC-3 and LNCaP prostate, and T98G glioblastoma tumor lines in both in vitro and in vivo studies. Oligos against the anti-apoptosis protein bcl-2 (MR4) are also efficient against PC-3 and LNCaP tumors in similar in vitro experiments." "To enhance activity, and also to introduce a derivative type of multifunctional oligo into this field, ''bispecifics'' were constructed containing two truncated complementary...
Source: Women's Health Weekly (2008-07-10)
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