Women's Health Weekly
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Breast Cancer
Study findings on breast cancer are outlined in reports from University of Helsinki
July 10th, 2008
"The ataxia- telangiectasia- mutated ( ATM) kinase is a key transducer of DNA damage signals within the genome maintenance machinery and a tumour suppressor whose germline mutations predispose to familial breast cancer. ATM signalling is constitutively activated in early stages of diverse types of human malignancies and cell culture models in response to oncogene- induced DNA damage providing a barrier against tumour progression," scientists writing in the journal Oncogene report. "As BRCA1 and BRCA2 are also components of the genome maintenance network and their mutations predispose to breast cancer, we have examined the ATM expression in human breast carcinomas...
Source: Women's Health Weekly (2008-07-10)
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