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Women's Health Weekly

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Breast Cancer



Investigators at National Institutes of Health publish new data on breast cancer



July 17th, 2008

"To evaluate the potential contribution of mutations in the BRCA1 and BRCA2 genes to male breast cancer (MBC), we expanded a previous study to screen a total of 261 Israeli men diagnosed with breast carcinoma," researchers in the United States report.

"A total of 21 BRCA2 6174delT and 8 BRCA1 185delAG mutations were found. Similar frequencies of BRCA1 and BRCA2 mutation carriers were found among Ashkenazi (12.8%) and non-Ashkenazi Jews (9.1 %)," wrote G. Chodick and colleagues, National Institutes of Health.

The researchers concluded: "The combined prevalence of BRCA1/BRCA2 founder mutations among Ashkenazi Jewish men is slightly higher than for...


Source: Women's Health Weekly (2008-07-17)

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