Women's Health Weekly
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Endometrial Cancer
Researchers from Mayo Clinic report details of new studies and findings in the area of endometrial cancer
July 17th, 2008
"Tight junction (TJ) proteins claudin-3 and claudin-4 may be differentially expressed in uterine serous papillary carcinoma (USPC), a rare form of endometrial cancer characterized by a particularly poor prognosis. Our aim was to determine the expression pattern and prognostic relevance of claudin-3 and claudin-4 in a large cohort of endometrial cancer patients of diverse histological type and stage," scientists in the United States report. "Claudin-3 and claudin-4 expression was studied in a cohort of 287 patients with endometrial cancer including 137 cases of USPC or clear-cell histology using immunohistochemistry. Patients were completely surgically staged. Outcome...
Source: Women's Health Weekly (2008-07-17)
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