Women's Health Weekly
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Human Papillomavirus
Research from University of Pittsburgh, Medical Department has provided new information about human papillomavirus
July 17th, 2008
According to recent research from the United States, "Human papillomaviruses (HPVs) are involved in the pathogenesis of cancer of the cervix (CaCx). MicroRNA (miRNA) expression analysis using Ambion (Austin, TX, USA) arrays showed that three miRNAs were over-expressed and 24 underexpressed in cervical cell lines containing integrated HPV-16 DNA compared to the normal cervix." "Furthermore, nine miRNAs were overexpressed and one underexpressed in integrated HPV-16 cell lines compared to the HPV-negative CaCx cell line C-33A. Based on microarray and/or quantitative realtime PCR and northern blot analyses, microRNA-218 (miR-218) was specifically underexpressed in...
Source: Women's Health Weekly (2008-07-17)
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