Women's Health Weekly
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Spectroscopy
New findings from Center for Satellite Applications and Research in the area of spectroscopy described
July 17th, 2008
According to recent research from Singapore, Singapore, "Surface plasmon resonance (SPR) spectroscopy has emerged as a powerful alternative to conventional biochemistry methods for studying protein-DNA interactions that involve recombinant proteins of known identity. There are, however, limited demonstrations of SPR detection of protein-DNA bindings in crude samples, e.g., cell extracts, where the challenge is to detect and identify specific DNA binding protein(s) among other protein components in a physiological setting." "We have developed a two-step antibody approach for an SPR study of estrogen receptor alpha (ER alpha)-DNA interactions, in which nuclear extracts...
Source: Women's Health Weekly (2008-07-17)
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