Women's Health Weekly
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Apoptosis Cell Biology
Studies from University of Kuopio yield new information about apoptosis cell biology
July 17th, 2008
Current study results from the report, 'Benzo(a)pyrene increases phosphorylation of p53 at serine 392 in relation to p53 induction and cell death in MCF-7 cells,' have been published. According to a study from Kuopio, Finland, "Although benzo(a)pyrene (BP) induces apoptosis in vitro in murine Hepa1c1c7 cells and in vivo indications of apoptosis in rat lung exist, related cellular mechanisms in human cells are not known. p53 protein participates in several apoptotic processes. We found that BP induces cell death in human MCF-7 breast adenocarcinoma cells at 48 and 72h but not in human A549 lung carcinoma cells." "BP did not induce measurable caspase-3-like protease...
Source: Women's Health Weekly (2008-07-17)
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