Women's Health Weekly
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Breast Cancer
Findings from Utah State University broaden understanding of breast cancer
July 24th, 2008
According to recent research published in the journal Molecular Cancer, "Telomerase expression is detectable in 81-95% of breast carcinomas and may serve as a therapeutic target. The objective of this study was to investigate repression of telomerase activity in primary ductal breast cancer cells through transcriptional regulation of the catalytic subunit hTERT." "We hypothesized that inhibition of telomerase expression could be achieved via Tat mediated protein transduction of the repressor protein E2F-1. Protein purification techniques were refined to yield biologically active Tat fusion proteins (TFPs) capable of transducing the breast cancer cell lines...
Source: Women's Health Weekly (2008-07-24)
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