Women's Health Weekly
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Breast Cancer
Investigators at Vanderbilt University target breast cancer
July 24th, 2008
"A polymorphism at codon 655 (ATC/isoleucine to GTC/valine [Ile(655)Val], rs1801200) in the transmembrane domain-coding region of human ERBB2 gene has been previously evaluated for its association with breast cancer risk with mixed results. We evaluated this polymorphism in association with breast cancer in a group of women who participated in a large-scale, population-based, case-control study of breast cancer in Shanghai, China, followed by an in vitro analysis of the function of this polymorphism," investigators in the United States report. "Genomic DNA from 3,012 patients with breast cancer and 3,004 healthy controls was examined for the Ile(655)Val polymorphism...
Source: Women's Health Weekly (2008-07-24)
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