Hypertrophic Cardiomyopathy

Researchers from Mayo Clinic describe findings in hypertrophic cardiomyopathy

Published in Women's Health Weekly, July 24th, 2008

" Hypertrophic cardiomyopathy (HCM) is a disease characterized by substantial genetic, morphologic, and prognostic heterogeneity. Recently, sex-related differences in HCM were reported, with women being older at diagnosis and exhibiting greater left ventricular outflow tract obstruction than men," scientists in the United States report.

"We sought to evaluate the influence of sex on the HCM phenotype in a large cohort of unrelated patients with genetically and morphologically classified HCM. Comprehensive genotyping of 13 HCM-susceptibility genes encoding myofilament and Z-disc proteins of the cardiac sarcomere was performed previously on 382 unrelated patients with...

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Source: Women's Health Weekly (2008-07-24)

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