Women's Health Weekly
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Breast Cancer
Reports outline breast cancer study results from University of Texas
July 24th, 2008
According to recent research from the United States, "The histone protein family member X (H2AFX) is important in maintaining chromatin structure and genetic stability. Genetic variants in H2AFX may alter protein functions and thus cancer risk." "In this case-control study, we genotyped four common single nucleotide polymorphisms (i.e., -1654A > G [rs643788], -1420G > A [rs8551], and -1187T > C [rs7759] in the H2AFX promoter region and 1057C > T [rs7350] in the 3' untranslated region (UTR)) in 467 patients with sporadic breast cancer and 488 cancer-free controls. All female subjects were non-Hispanic whites aged <= 55 years. We found that significantly...
Source: Women's Health Weekly (2008-07-24)
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