Women's Health Weekly
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Breast Cancer
Research conducted at M. Lauss and co-researchers has updated our knowledge about breast cancer
July 24th, 2008
According to recent research from Seibersdorf, Austria, "Extensive efforts have been undertaken to discover genes relevant for breast cancer prognosis. Yet, in current opinion, with little overlap in findings." "We aimed to reanalyze molecular prediction of breast cancer recurrence. From 44 published gene lists relevant for breast cancer prognosis, we extracted 374 genes, which, besides other quality criteria, are recorded at least twice. From eight published microarray datasets, a single dataset of 1,067 breast cancer patients was created, using transformation to 'probability of expression' scale. For recurrence analysis, the Cox proportional hazards model was applied....
Source: Women's Health Weekly (2008-07-24)
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