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Women's Health Weekly

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Chlamydia



Research in the area of chlamydia reported from University of California



July 31st, 2008

According to a study from the United States, "To elucidate the mechanisms involved in early events in Chlamydia trachomatis infection, we conducted a large scale unbiased RNA interference screen in Drosophila melanogaster S2 cells. This allowed identification of candidate host factors in a simple non-redundant, genetically tractable system."

"From a library of 7,216 double stranded RNAs (dsRNA), we identified,226 host genes, including two tyrosine kinases, Abelson (AbI) kinase and PDGF- and VEGF-receptor related (Pvr), a homolog of the Platelet-derived growth factor receptor ( PDGFR). We further examined the role of these two kinases in C. trachomatis binding and...


Source: Women's Health Weekly (2008-07-31)

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