Women's Health Weekly
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Chlamydia
Studies from C. Delevoye and co-authors have provided new information about chlamydia
July 31st, 2008
"Many intracellular pathogens rely on host cell membrane compartments for their survival. The strategies they have developed to subvert intracellular trafficking are often unknown, and SNARE proteins, which are essential for membrane fusion, are possible targets," scientists in Paris, France report. "The obligate intracellular bacteria Chlamydia replicate within an intracellular vacuole, termed an inclusion. A large family of bacterial proteins is inserted in the inclusion membrane, and the role of these inclusion proteins is mostly unknown. Here we identify SNARE-like motifs in the inclusion protein IncA, which are conserved among most Chlamydia species. We show that...
Source: Women's Health Weekly (2008-07-31)
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