Women's Health Weekly
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Oncogenic Virus
Research by R. Catarino and colleagues in oncogenic virus provides new insights
July 31st, 2008
"Cyclin D1 (CCND1) is a key regulatory protein at the G1/S checkpoint of the cell cycle. The purpose of our study was to assess the role of CCND1 genotypes influencing the age of onset of oncogenic virus-associated neoplasia," researchers in Oporto, Portugal report. "We conducted a hospital-based case-control study of 581 individuals, including 247 controls and 334 cases (108 nasopharyngeal and 226 cervical cancer cases). The polymorphism analysis was performed in blood samples by PCR-RFLP methodology. Age-adjusted logistic regression analysis indicates that individuals carrying two G-alleles have an increased genetic susceptibility for the development of oncogenic...
Source: Women's Health Weekly (2008-07-31)
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