Women's Health Weekly
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Acute Leukemia Genetics
Investigators at Catholic University of Korea, Department of Pathology target acute leukemia genetics
July 31st, 2008
Scientists discuss in 'Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers' new findings in acute leukemia. "The aim of this study was to see whether JAK1, JAK3, and TYK2 genes are altered in human cancers. We analyzed 494 tissues from 186 acute adulthood leukemias, 30 multiple myelomas, and 278 common solid cancers, including 90 breast, 47 gastric, 47 colon, 47 lung, and 47 hepatocellular carcinomas by single-strand conformation polymorphism analysis," researchers in Seoul, Korea report. "Overall, we found six JAK1 mutations (four in acute leukemias, one in a lung carcinoma, and one in a breast carcinoma) and three JAK3 mutations (two in breast...
Source: Women's Health Weekly (2008-07-31)
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