Women's Health Weekly
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Breast Cancer Cell Biology
Findings from University of Maryland, Department of Pathology in breast cancer cell biology reported
July 31st, 2008
Current study results from the report, 'Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1,' have been published. According to recent research from the United States, "The ErbB2/3 heterodimer plays a critical role in breast cancer genesis and progression. EBP1, an ErbB3 binding protein, inhibits breast cancer growth but its effects on ErbB3 ligand mediated signal transduction or ErbB receptors is not known." "We report here that ectopic expression of EBP1 in MCF-7 and AU565 breast cancer cell lines inhibited HRG-induced proliferation. ErbB2 protein levels were substantially decreased in EBP1 transfectants, while ErbB3...
Source: Women's Health Weekly (2008-07-31)
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