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Women's Health Weekly

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Breast Cancer Genetics



Studies from Translational Genomics Research Institute add new findings in the area of breast cancer genetics



July 31st, 2008

New research, 'The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity,' is the subject of a report. According to a study from the United States, "Genomic characterization is beginning to define a molecular taxonomy for breast cancer; however, the molecular basis of invasion and metastasis remains poorly understood. We report a pivotal role for the fibroblast growth factor-inducible 14 (Fn14) receptor in this process."

"We examined whether Fn14 and its ligand tumor necrosis factor-like weak inducer of apoptosis (TWEAK) were expressed in breast tumors and whether deregulation...


Source: Women's Health Weekly (2008-07-31)

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