Women's Health Weekly
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Breast Cancer
Findings from Herlev University provide new insights into breast cancer
August 7th, 2008
According to recent research published in the Journal of Clinical Oncology, " Truncating and missense mutations in the ATM gene, which cause insufficient DNA damage surveillance, allow damaged cells to proceed into mitosis, which eventually results in increased cancer susceptibility. We tested the hypotheses that ATM Ser49Cys and ATM Ser707Pro heterozygosity increase the risk of cancer overall, of breast cancer, and of 26 other cancer subtypes in the general population." "Patients and Methods We genotyped 10,324 individuals from the Danish general population who were observed prospectively for 36 years, during which 2,056 developed cancer. Multifactorially...
Source: Women's Health Weekly (2008-08-07)
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