Women's Health Weekly
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Breast Cancer
Investigators at St. Mary's Hospital target breast cancer
August 7th, 2008
According to recent research published in the journal Familial Cancer, "64 families with a history of male breast cancer aged 60 or less or with a family history of male and female breast cancer were screened for the presence of BRCA1 and BRCA2 mutations. Seventeen pathogenic BRCA2 and four BRCA1 mutations were identified (34%) in samples from an affected family member." "All but one of the mutations segregated with disease where samples were available and pedigree structure permitted. Despite high sensitivity of mutation testing only 64% of families fulfilling BCLC criteria had an identifiable pathogenic mutation," wrote D.G.R. Evans and colleagues, St. Mary's...
Source: Women's Health Weekly (2008-08-07)
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