Women's Health Weekly
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Breast Cancer
New breast cancer research from T.H. Kim and colleagues discussed
August 7th, 2008
According to recent research published in the journal Histopathology, "Claudin 2 (CLDN2) is a family of integral membrane tight junctions. The aim was to determine the influence of CLDN2 expression on tumour behaviour and its role in breast carcinogenesis." "Thirty-seven invasive breast carcinomas and corresponding normal breast tissues were examined for CLDN2 protein and mRNA expression using Western blotting and semiquantitative reverse transcriptase-polymerase chain reaction. The expression of CLDN2 protein in 118 cases of breast carcinoma was further studied with immunohistochemistry and related to various clinicopathological parameters. CLDN2 protein...
Source: Women's Health Weekly (2008-08-07)
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