Women's Health Weekly
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Breast Cancer
New breast cancer study findings have been reported by scientists at Baylor College of Medicine, College of Medicine
August 7th, 2008
According to a study from the United States, "Using a syngeneic p53-null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified, by limiting dilution transplantation and in vitro mammosphere assay, a Lin(-)CD29(H)CD24(H) subpopulation of tumor-initiating cells. Upon subsequent transplantation, this subpopulation generated heterogeneous tumors that displayed properties similar to the primary tumor." "Analysis of biomarkers suggests the Lin-CD29(H)CD24(H) subpopulation may have arisen from a bipotent mammary progenitor. Differentially expressed genes in the Lin(-)CD29(H)CD24(H) mouse mammary gland tumor-initiating cell population...
Source: Women's Health Weekly (2008-08-07)
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