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Women's Health Weekly

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Breast Cancer



Researchers from University of Melbourne detail new studies and findings in the area of breast cancer



August 7th, 2008

"Mutations in the DNA mismatch repair gene MSH2 lead to increased replication error and microsatellite instability and account for a substantial proportion of hereditary non-polyposis colorectal cancer (Lynch syndrome). A recent international collaborative genome-wide linkage scan (GWS) for breast cancer susceptibility loci found some evidence for there being a breast cancer susceptibility gene in a genomic region on chromosome 2p close to MSH2," scientists in Melbourne, Australia report.

"We sought to investigate the possibility that mutations in MSH2 might explain the multiple cases of breast cancer in some families that were included in the international GWS. DNA...


Source: Women's Health Weekly (2008-08-07)

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