Women's Health Weekly
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Breast Cancer
Study findings from V. Cappelletti et al provide new insights into breast cancer
August 7th, 2008
"This study aimed to define a gene expression profile associated with response to anti-estrogen treatment in estrogen receptor alpha (ER alpha)-positive breast cancer from elderly patients and to identify possible candidate genes associated with resistance by detecting those modulated by treatment. Using cDNA microarrays containing 16 702 unique clones, 21 pre-treatment and 11 paired post-treatment samples collected in a neo-adjuvant toremifene trial on elderly patients with operable and locally advanced ER alpha-positive breast cancer were profiled," scientists in Milan, Italy report. "Gene expression profiles generated from pre-treatment samples were correlated with...
Source: Women's Health Weekly (2008-08-07)
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