University of California - San Diego

Discovery of a new signaling mechanism may lead to novel anti-inflammatory therapy

Published in Women's Health Weekly, August 7th, 2008

A team of researchers at the University of California, San Diego School of Medicine has uncovered a new signaling mechanism used to activate protein kinases that are critical for the body's inflammatory response. Their work will be published in the July 18 online edition of Science (Science Express.).

"In addition to helping explain the basic mechanisms of transmembrane receptor signaling, these results may identify a potential therapy for interfering with inflammation," said Michael Karin, Ph.D., professor of pharmacology and pathology in UC San Diego's Laboratory of Gene Regulation and Signal Transduction.

The tumor necrosis factor (TNF) receptor...

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Source: Women's Health Weekly (2008-08-07)

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