Women's Health Weekly
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Breast Cancer
New breast cancer study results reported from University of Porto
August 14th, 2008
"Changes in junctional catenin expression may compromise cadherin-mediated adhesion, increasing cell malignant properties such as invasive and metastatic abilities. Altered expression of alpha-, beta-, gamma- and p120-catenin has been reported to be associated with E-cadherin loss or decreased expression, in both breast carcinomas and breast cancer cell lines," scientists in Oporto, Portugal report. "To investigate the expression and subcellular localisation of p120- and beta-catenin in a series of human invasive breast carcinomas, and correlate it with biological markers and clinicopathological parameters. Both catenins frequently exhibited a reduced membranous or...
Source: Women's Health Weekly (2008-08-14)
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