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Women's Health Weekly

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Breast Cancer



Research conducted at K.B. Meyer and co-authors has provided new information about breast cancer



August 14th, 2008

According to recent research from Cambridge, the United Kingdom, "The recent whole-genome scan for breast cancer has revealed the FGFR2 (fibroblast growth factor receptor 2) gene as a locus associated with a small, but highly significant, increase in the risk of developing breast cancer. Using fine-scale genetic mapping of the region, it has been possible to narrow the causative locus to a haplotype of eight strongly linked single nucleotide polymorphisms (SNPs) spanning a region of 7.5 kilobases (kb)in the second intron of the FGFR2 gene."

"Here we describe a functional analysis to define the causative SNP, and we propose a model for a disease mechanism. Using gene...


Source: Women's Health Weekly (2008-08-14)

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