Women's Health Weekly
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Breast Cancer
New breast cancer study findings recently were reported by researchers at University of Regensburg
August 21st, 2008
According to recent research from Regensburg, Germany, "Estrogen receptor beta gene codes for a variety of transcript isoforms resulting from alternative splicing, which are expressed both in mammary gland and in breast cancer cells. We studied the function of two exon-deleted ER beta isoforms recently identified by our group in comparison to ER beta 1 in regulation of growth, apoptosis and gene expression of two breast cancer cell lines with different ER alpha status." "Overexpression of ER beta 1, but not of the exon-deleted variants exerted strong antitumoral effects both on ER alpha-positive MCF-7 and ER alpha-negative SK-BR-3 cells. ER beta 1 overexpression slowed...
Source: Women's Health Weekly (2008-08-21)
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