Women's Health Weekly
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Breast Cancer
Reports from M. Schmidt and co-researchers add new data to research in breast cancer
August 21st, 2008
"Estrogen receptor (ER) expression and proliferative activity are established prognostic factors in breast cancer. In a search for additional prognostic motifs, we analyzed the gene expression patterns of 200 tumors of patients who were not treated by systemic therapy after surgery using a discovery approach," investigators in Cologne, Germany report. "After performing hierarchical cluster analysis, we identified coregulated genes related to the biological process of proliferation, steroid hormone receptor expression, as well as B-cell and T-cell infiltration. We calculated metagenes as a surrogate for all genes contained within a particular cluster and visualized the...
Source: Women's Health Weekly (2008-08-21)
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