Women's Health Weekly
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Breast Cancer
Reports outline breast cancer study results from C. Wang et al
August 21st, 2008
According to recent research from Tianjin, People's Republic of China, "The 1100delC CHEK2 allele has been associated with a 1.4-to 4.7-fold increased risk of breast cancer in women carrying this mutation. Our study investigated the frequency of this allele in a Chinese population." "Using touchdown polymerase chain reaction, we sequenced the CHEK2.1100delC mutation in 74 breast cancer patients with a family history of breast cancer and 50 control subjects. We did not find the CHEK2.1100delC mutation in any of the Chinese subjects. However, another missense mutation, 1111C > T (His371Tyr), was found in a familial breast cancer patient, but not in any other subjects....
Source: Women's Health Weekly (2008-08-21)
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