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Women's Health Weekly

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Breast Cancer



Research reports from University of British Columbia provide new insights into breast cancer



August 21st, 2008

According to a study from Vancouver, Canada, " Estrogen receptor (ER) expression is routinely assessed by immunohistochemistry (IHC) in breast carcinoma. Our study compares visual scoring of ER in invasive breast cancer by histopathologists to quantitation of staining using a fully automated system."

"Materials and methods A tissue microarray was constructed from 4,049 cases (3,484 included in analysis) of invasive breast carcinoma linked to treatment and outcome information. Slides were scored independently by two pathologists and scores were dichotomised, with ER positivity recognized at a cut-off of > 1% positive nuclei. The slides were scanned and analyzed with...


Source: Women's Health Weekly (2008-08-21)

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