Women's Health Weekly
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Breast Cancer
Investigators at Nanjing Medical University publish new data on breast cancer
August 28th, 2008
According to recent research from Nanjing, People's Republic of China, "Radiation can activate the phosphatidylinositol 3-kinase/Akt pathway and cannot downregulate survivin expression in breast cancer cells. Deguelin induces apoptosis in breast cancer cells by inhibiting pAkt and survivin expression." "In this study, we assessed the effect of deguelin on radiosensitization of human breast cancer cells and its possible mechanism. Deguelin and radiation were administrated in MDA-MB-231 human breast cancer cells. The cytotoxic interactions and mutual influences between these 2 modalities were analyzed by a series of assays including clonogenic,flow cytometric, and Western...
Source: Women's Health Weekly (2008-08-28)
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