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Women's Health Weekly

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Breast Cancer



Northwestern University details research in breast cancer



August 28th, 2008

According to recent research published in the journal Clinical & Experimental Metastasis, "Metastasis is a complicated process that depends largely on the interaction of primary tumors and the local host environment. In this study, we have established a new mouse model to mimic the process of tumor metastasis in breast cancer patients."

"TM40D-MB mouse mammary tumor cells were transplanted to the mammary glands of syngeneic mice. Mammary tumors developed in the glands in situ and were metastatic to bone with over 53% efficiency. We compared the gene expression profile of high (TM40D-MB) vs. low metastatic (TM40D) tumor cells using Affymetrix microarray chips....


Source: Women's Health Weekly (2008-08-28)

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