Women's Health Weekly
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Breast Cancer
Research results from S. Raulic and co-authors update knowledge of breast cancer
August 28th, 2008
"Stanniocalcin 1 (STC1) and STC2 are secreted, homodimeric glycoproteins that share 30% amino acid sequence identity. Breast turnout gene profiling studies have demonstrated significantly upregulated STC2 expression in hormone-responsive positive breast tumours; therefore, the purpose of this study was to investigate STC2 hormonal regulation and function in breast cancer cells," researchers in London, Canada report. "Here we report that STC2 is expressed in a number of human breast cancer cell lines, regardless of their oestrogen (E-2) and progesterone (P4) receptor status, and its expression is readily detectable in human and mouse mammary gland tumours. Besides E-2,...
Source: Women's Health Weekly (2008-08-28)
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