Women's Health Weekly
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Canadian Medical Association Journal
Proton pump inhibitors increase risk of bone fractures
August 28th, 2008
Patients who use proton pump inhibitors for 7 or more years to treat reflux, peptic ulcers and other conditions are at greater risk of osteoporosis-related fractures, according to this large observational study, http://www.cmaj.ca/press/pg319.pdf, of 15,792 patients published in CMAJ. There is specifically an increased risk of hip fracture after 5 years of continuous exposure and an increased risk of any fracture after 7 years continuous exposure. Short-term exposure did not appear to increase risk of fractures. Proton pump inhibitors — a class of drugs commonly prescribed to control and prevent symptoms and complications of peptic ulcer disease and...
Source: Women's Health Weekly (2008-08-28)
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