Women's Health Weekly
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Breast Cancer
Study results from University of London, Imperial College update understanding of breast cancer
August 28th, 2008
According to recent research from London, the United Kingdom, "17 beta-Estradiol (E-2) is a key regulatory steroid hormone that is involved in the control of a number of developmental and other functions. The aim of the present work was to identify estrogen-dependent proteomic changes by determining the levels of expressed proteins in MCF-7 human breast cancer cells following treatment with E-2." "A number of methods exist for differential analysis of complex proteomic mixtures. Here, a label-free mass spectrometric approach comparing the ion intensities of tryptic peptides was adopted, which was combined with prefractionation of whole cell lysate proteins by 1-D...
Source: Women's Health Weekly (2008-08-28)
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