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Women's Health Weekly

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Cancer



Recent findings from University of Rochester highlight research in cancer



August 28th, 2008

According to recent research from the United States, " To identify and mathematically model molecular predictors of response to the enediyne chemotherapeutic agent, neocarzinostatin, in nervous system cancer cell lines. Human neuroblastoma, breast cancer, glioma, and medulloblastoma cell lines were maintained in culture."

"Content of caspase-3 and Bcl-2, respectively, was determined relative to actin content for each cell line by Western blotting and optical densitometry. For each cell line, sensitivity to neocarzinostatin was determined. Brain tumor cell lines were stably transfected with human Bcl-2 cDNA cloned into the pcDNA3 plasmid vector. In human tumor cell...


Source: Women's Health Weekly (2008-08-28)

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