Women's Health Weekly
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Breast Cancer
Investigators at Nanjing Medical University zero in on breast cancer
September 4th, 2008
According to a study from Nanjing, People's Republic of China, "Epidermal growth factor (EGF), a potent mitogenic peptide, plays an important role in the development of cancers, including breast cancer. Previous studies showed that plasma EGF levels may influence the risk of cancer." "In the current study, we hypothesized that genetic variants in the promoter region of EGF may influence plasma EGF levels and therefore are associated with breast cancer susceptibility. We genotyped three EGF polymorphisms (G61A, G-1380A, and A-1744G) in the promoter region by PCR-RFLP and measured plasma EGF levels using an enzyme immunoassay in a case-control study of Chinese women. We...
Source: Women's Health Weekly (2008-09-04)
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