Women's Health Weekly
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Breast Cancer
New breast cancer research from McGill University discussed
September 4th, 2008
"High-risk human papillomaviruses (HPVs) could be important risk factors for breast carcinogenesis and metastasis. Based on this hypothesis, we recently studied the effect of E6/E7 onco-proteins of high-risk HPV type 16 in two non-invasive human breast cancer cell lines, BT20 and MCF7; we reported that E6/E7 converts these cell lines to invasive cells," scientists writing in the British Journal of Cancer report. "This is accompanied by an overexpression of Id-1, which is an important regulator of breast metastasis. In this investigation, we examined the presence of high-risk HPVs ( 16, 18, 31, 33 and 35) and the expression of their E6 onco-protein as well as...
Source: Women's Health Weekly (2008-09-04)
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