Women's Health Weekly
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Breast Cancer
Recent studies by S. Sangrajrang and co-authors add new data to breast cancer findings
September 4th, 2008
According to recent research from Bangkok, Thailand, "DNA repair plays an important role in tumor development. The base excision repair (BER) pathway mainly removes DNA damage caused by ionizing radiation and reactive oxidative species." "Here, we examined possible associations between polymorphisms in three important BER genes (OGG1 Ser326Cys, APEX1 Asp148Glu, XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln) and breast cancer incidence in Thai women. The study population consisted of 507 breast cancer cases and 425 controls. Odds ratios (OR) were adjusted by multivariate logistic regression analysis for age, body mass index, age at menarche, family history of breast...
Source: Women's Health Weekly (2008-09-04)
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