Women's Health Weekly
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Breast Cancer
Research in the area of breast cancer reported from M.T. Epping and colleagues
September 4th, 2008
According to a study from Netherlands, "The tumour antigen PReferentially expressed Antigen of MElanoma ( PRAME) is expressed in a variety of malignancies, including breast cancer. We have analysed PRAME gene expression in relation to clinical outcome for 295 primary breast cancer patients." "Kaplan-Meier survival curves show a correlation of PRAME expression levels with increased rates of distant metastases and decreased overall patient survival. This correlation existed both for the entire patient group (n=295) and for the subgroup of patients (n=185) who did not receive adjuvant chemotherapy. Multivariable analysis indicated that PRAME is an independent marker of...
Source: Women's Health Weekly (2008-09-04)
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