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Women's Health Weekly

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Breast Cancer



Research reports on breast cancer from Duke University provide new insights



September 4th, 2008

" Breast cancer arising in young women is correlated with inferior survival and higher incidence of negative clinicopathologic features. The biology driving this aggressive disease has yet to be defined," investigators in the United States report.

"Patients and Methods Clinically annotated, microarray data from 784 early-stage breast cancers were identified, and prospectively defined, age-specific cohorts (young: <= 45 years, n = 200; older: >= 65 years, n = 211) were compared by prognosis, clinicopathologic variables, mRNA expression values, single-gene analysis, and gene set enrichment analysis (GSEA). Univariate and multivariate analyses were performed. Using...


Source: Women's Health Weekly (2008-09-04)

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