Women's Health Weekly
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Breast Cancer
New breast cancer findings from M. Yu and co-researchers published
September 11th, 2008
According to recent research from Tianjin, People's Republic of China, "Mitochondrial DNA (mtDNA) is known for its high frequencies of polymorphisms and mutations. The non-coding displacement (D)-loop, especially a mononucleotide repeat (poly-C) between 303 and 315 nucleotides (D310), has been recently identified as a frequent hotspot of mutations in human neoplasia, including breast cancer." "To further explore the sequence variations of mitochondrial D-loop region in familial breast cancer and their possible associations with breast cancer risk, PCR-SSCP and direct DNA sequencing methods were used to detect the variants of the mtDNA D-Loop in 23 familial breast cancer...
Source: Women's Health Weekly (2008-09-11)
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