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Women's Health Weekly

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Breast Cancer



New breast cancer research has been reported by scientists at Sun Yat-Sen University



September 11th, 2008

"The purpose of this study was to reveal the effects of hepatocyte growth factor (HGF) variants on human breast cancer cells and the differential signaling pathways of the variants in controlling cell proliferation and invasion. Four HGF variants (NK1, NK2, NK3, and NK4) were created by gene engineering, and the variant DNA fragments were cloned into pGEM-T for DNA sequencing and then transferred to a pTrcHis-A plasmid for expression," researchers in Kaohsiung, Taiwan report.

"Recombinant proteins were purified from Escherichia coli, and a series of assays, including cell proliferation and invasion were carried out. Phosphorylated components in the HGF-c-Met and STAT...


Source: Women's Health Weekly (2008-09-11)

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