Women's Health Weekly
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Breast Cancer
Research reports from University of Pisa provide new insights into breast cancer
September 11th, 2008
"Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell membrane rearrangements for cell motility to be enacted," investigators in Pisa, Italy report. "We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA), drospirenone (DRSP) and nestorone (NES) alone or with 17 beta-estradiol (E2) on T47-D breast cancer cell migration and invasion and we linked some of these actions to the regulation of the actin-regulatory protein, moesin and to cytoskeletal remodeling. Breast cancer cell horizontal...
Source: Women's Health Weekly (2008-09-11)
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