Women's Health Weekly
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Cervical Cancer
Studies from M. Narisawasaito and co-researchers yield new data on cervical cancer
September 11th, 2008
"Human papillomaviruses (HPV) are believed to be the primary causal agents for development of cervical cancer, and deregulated expression of two viral oncogenes E6 and E7 in basal cells, mostly by integration, is considered to be a critical event for disease progression. However, lines of evidence suggest that, besides expression of E6 and E7 genes, additional host genetic alterations are required for cancer development," scientists in Tsukiji, Japan report. "To directly test this hypothesis, we first transduced HPV16 E6 and E7 with or without hTERT into several lines of normal human cervical keratinocytes (HCK) from independent donors and then searched for additional...
Source: Women's Health Weekly (2008-09-11)
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