Women's Health Weekly
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Endometrial Cancer
Study data from J.V. Lacey et al provide new insights into endometrial cancer
September 11th, 2008
According to recent research from the United States, "Inactivation of PTEN tumor suppressor gene is common in endometrial carcinoma and its precursor, atypical endometrial hyperplasia (Ell). We compared PTEN expression via inummohistochemistry in endometrial biopsies diagnosed as EH in 138 cases, who were diagnosed with EH and then endometrial carcinoma at least I year later (median, 6 years), and 241 individually matched controls, who were diagnosed with EH but did not progress to carcinoma during equivalent follow-up." "We assessed PTEN status (normal versus null) in index biopsies containing EH to estimate the relative risk (RR) of developing endometrial carcinoma up...
Source: Women's Health Weekly (2008-09-11)
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