Lipodystrophy

Recent findings from National Institutes of Health highlight research in lipodystrophy

Published in Women's Health Weekly, September 18th, 2008

According to recent research from the United States, "Lipodystrophy is a rare condition causing severe insulin resistance and frank diabetes. Depot medroxyprogesterone acetate (DMPA), a commonly used contraceptive, may worsen glucose tolerance in diabetics and those with lipodystrophy."

"A young woman with generalized lipodystrophy, who previously required greater than 1,000 units of insulin daily, had a normal hemoglobin A1c on leptin and metformin only. After an injection of DMPA, she developed severe hyperglycemia. Her levels returned to near normal only with extremely high doses of insulin (up to 1,700 units/d) and increased doses of leptin and metformin....

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Source: Women's Health Weekly (2008-09-18)

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